I assume that each organism which the Creator educed was stamped with an indelible specific character, which made it what it was, and distinguished it from everything else, however near or like. I assume that such character has been, and is , indelible and immutable..
Philip Henry Gosse Omphalos: An Attempt to Unite the Geological Knot (1857),111.
This is a beautiful saying by P.H.GOSSE , where he is highlighting that specific character of individual is responsible for his peculiar identity. In fact, it is tragically easy for a patient to become merely the repository in which a disease or a syndrome has chosen to manifest its particular silhouette. That is why we say – We treat the patient not the disease.i.e.We have to treat the person in disease, rather than the disease.
Now, I would like to make it more understandable on basis of Gene functioning: Life starts with fertilisation of ovum and sperm. These ovum and sperm contains all the genes encoded within in 50:50 ratio. (Guyton in his physiology book (textbook of medical physiology,11th edition,ch-3) has mentioned if there is any control of life, it is the gene – DNA system.The Gene-DNA system is the basic control of life. Genes are not only encoded with physical structures, but also the mental character of a person.
The Gene controls all the systems by making specific proteins and thus performs specific functions in the cell. Two types of proteins are formed : Enzymatic proteins and Structural proteins. But everything is not inherited. We also acquire some characters. So, our genes are acquired as well as inherited characters. The proteins synthesized by R.N.A. are expressed in cell- tissue – system. And our intellect, will, emotions etc. Thus, physical as well as mental general make up of every individual arises from Genome.
1.ENZYMATIC PROTEINS- These proteins are responsible for mental constitution of a person. Like his temperament,diathesis,nature,intelligence,desires,aversions,etc.
2.STRUCTURAL PROTEINS- These proteins are responsible for physical structure of an individual Eg- height,contour,face cut,eye colour, texture of hair etc.
So, every human being is a resultant of the combination of individual’s unique genetic makeup and environment. And every individual is different from one another. This is what our Master said 200 yrs back in THEORY OF INDIVIDUALIZATION, which is now proved scientifically.To understand individualization we must personify persons ; taking his Physical,Mental constitution etc and tolerance to environmental factors.
Aphorism-138 : ‘’All the sufferings………………………………………………………………………………………….. That this individual is, by the virtue of his peculiar constitution, particularly disposed to have such symptoms excited in him……………………………………………’’
Now, I would cite few examples to make you understand ,how an individual is prone to certain diseases due to his peculiar individuality.
Let me give some examples of Epidemiologic factors to Neoplasia in this regard.
Eg. Of FAMILIAL AND GENETIC FACTORS:
FAMILIAL POLYPOSIS COLI- By age of 50 years , almost 100% cases of familial polyposis coli develop cancer of colon.
RETINOBLASTOMA- About 40% of retinoblastoma are familial and show a autosomal dominant inheritance.genetic carriers of such genetic composition have 10,000 times higher risk of developing retinoblastoma which is often bilateral.
Eg. Of RACIAL AND GEOGRAPHICAL FACTORS:
1.White Europeans and americans develop most commonly malignancies of the lung,breast and colon.liver cancer is uncommon in these races. 2.Japanese have five times higher incidence of carcinoma of the stomach than the americans. 3.South east Asians,especially of chinese origin develop nasopharyngeal cancer more commonly.
Eg. Of ENVIRONMENTAL AND CULTURAL FACTORS:
Alcohol abuse predisposes to the development of cancer of oropharynx,larynx,oesophagus and liver. Penile cancer is rare in the Muslims as they are customarily circumcised.carcinogenic component of smegma appear to play a role in the etiology of penile cancer. Betel nut cancer of cheek and tongue is quite common in some parts of india due to habitual practice of keeping the bolus of paan in particular place in mouth for a long time.
We all are familiar with Diabetes Mellitus.The prevalemce of diabetes is increasingly sharply in the developing world.india and china being the largest contributers to the world’s diabetic load.i want to focus here on the pathogenesis of diabetes:
GENETIC SUSCEPTIBILITY- Epidemiologic studies, such as those demonstrating higher concordance rates for disease in monozygotic vs dizygotic twins,have convincingly established a genetic basis for type1 diabetes. More recently, genomewide association studies have identified multiple genetic susceptibility loci for TYPE 1 DIABETES,as well as TYPE 2 DIABETES.over a dozen susceptibility loci for type1 diabetes are now known. Of these,the far most important is the HLA locus on chromosome 6p21; according to some estimates,the HLA locus contributes as much as 50% of the genetic susceptibility to type 1 diabetes. 90-95% of Caucasians with this disease have either a HLA-DR3 or HLA-DR4 haplotype, in contrast to about 40% of normal subjects.
ENVIRONMENTAL FACTORS- there are environmental factors,especially viral infections,may be involved in triggering islet cell destruction in TYPE 1 DIABETES. Epidemiologic associations have been reported between type 1 diabetes and infection with mumps,rubella,coxsackie B, or cytomegalo virus,among others. OBESITY AND INSULIN RESISTANCE- The epidemiologic association of obesity with TYPE 2 DIABETES has been recognised for decades,with visceral obesity is observed in greater than 80% of patients. Obesity has profound effects on sensitivity of tissue to insulin, and as consequence,on systemic glucose homoeostasis. Insulin resistance is present even in simple obesity unaccompanied by hyperglycaemia,indicating a fundamental abnormality of insulin signalling in states of fatty excess. The risk for diabetes increases as body mass index (a measure of body fat content) increases.It is not only the absolute amount but also the distribution of body fat that has an effect on insulin sensitivity: central obesity (abdominal fat) is more likely to be linked with insulin resistance than are peripheral (gluteal/subcutaneous) fat deposits. obesity can adversely impact insulin sensitivity in numerous ways. As ever day is different from the other day so does every human being differs from one another . It is important to individualize the person; this can only be done if the physician takes the entire case unprejudiously from the point of beginning in the holistic manner. It is the process of perceiving as to how a patient as a person evolved and distinguished himself as a unique entity. Hence, individuality forms the central axis of homoeopathic philosophy.
CONCLUSION: So it is Patient who is Personified rather than the disease.Hence, we need to correlate our entire homoeopathic principles theories and philosophy in similar manner to make it more scientific andprecise in present and future era.
Aphorism-3: ‘’If the physician clearly perceives what is to be cured in disease, that is to say, in every individual case of disease………………………………………………………………………………and he is a true practioner of healing art.’’
Text book of Physiology;GUYTON ; 11th edition
Pathologic basis of disease ;ROBBINS AND COTRAN ; 8th edition
Textbook of Pathology ;HARSH MOHAN ; 6th edition
Internet : (http://www.drvithal.com/article-details.php?pid=10) Posted from Bakson Homoeopathic Medical College